It is important to know that the abnormalities in the way our body handles blood glucose start to develop several years before diagnosis without clear overt signs. The start of the problem is thought to be related to the hormone insulin. Due to some genetic or environmental reasons insulin does not work effectively in the body. Insulin secretion becomes then affected. Problems with insulin action and secretion lead to the buildup of glucose in the blood and after several years diabetes is diagnosed. It is of outmost importance to take action within these years in order to be effective in preventing diabetes The major factors play a role in developing the disease: